⚡ 30-second answer: Nihon Chouzai / Ainz & Tulpe / Cocokara Fine / Welcia / Matsumoto Kiyoshi are the top 5. Prescription drugs require a doctor's prescription, picked up at a pharmacy. With National Health Insurance, patient pays 30% — roughly ¥1,000-¥15,000/month. Personal imports from overseas may need a Yakkan Shoumei (drug import certificate), and psychotropic / narcotic drugs require advance declaration. English-friendly pharmacies cluster in central Tokyo, Osaka, and Kyoto.
Quick Reference
Value
Co-pay (with insurance)
30%
Monthly estimate
¥1,000-¥15,000
Uninsured
Full price (~3.3x)
Prescription validity
4 days
OTC also sold
Yes at major stores
Credit cards
Accepted at major stores
Last verified
June 2026
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Contents📖 ~5 min read
30-second answer
Japan's pharmacy system requires you to bring a prescription from a doctor to a pharmacy within 4 days. Holders of National Health Insurance (kokuho) or employee insurance pay only 30%. Long-staying foreigners enrolled in kokuho typically spend ¥1,000-¥15,000/month (varies by condition). Nihon Chouzai runs 700+ branches mostly near hospitals; Ainz & Tulpe combines prescriptions with cosmetics in central districts; and Cocokara Fine / Welcia / Matsumoto Kiyoshi are drugstores that also dispense prescriptions and sell OTC items. English-friendly pharmacies cluster in central Tokyo (Roppongi, Azabu, Shinjuku, Ginza), Osaka (Umeda), and Kyoto (Gion). Personal imports from overseas may require a Yakkan Shoumei, and psychotropic / narcotic drugs (sleeping pills, ADHD meds, opioids) are either banned or require advance declaration. Only prescriptions written by doctors licensed in Japan are valid; overseas prescriptions cannot be filled.
Top 15 pharmacies
#
Pharmacy
Area
Strength
1
Nihon Chouzai Roppongi
Roppongi
English, near embassies
2
Nihon Chouzai Azabu-Juban
Azabu-Juban
English, many foreigners
3
Ainz & Tulpe Shinjuku East
Shinjuku
Flagship, prescriptions + cosmetics
4
Ainz & Tulpe Ginza
Ginza
English, many tourists
5
Cocokara Fine Shibuya Scramble
Shibuya
Near station, strong OTC
6
Welcia Shinjuku 3-chome
Shinjuku
Some 24-hour branches
7
Matsumoto Kiyoshi Ueno Ameyoko
Ueno
Tourist-focused, tax-free
8
Matsumoto Kiyoshi Shibuya Center-gai
Shibuya
Tourist-focused, tax-free
9
Sugi Pharmacy Umeda
Osaka Umeda
Kansai major, English
10
Qol Pharmacy Kyoto Gion
Kyoto Gion
Tourist support
11
Kokumin Drug Shinsaibashi
Osaka Shinsaibashi
English, tourists
12
Sundrug Ikebukuro East
Ikebukuro
Low prices, strong OTC
13
Tsuruha Drug Sapporo
Sapporo
Hokkaido leader
14
Drug Seims Nagoya Sakae
Nagoya Sakae
Chubu leader
15
Oga Pharmacy Fukuoka Tenjin
Fukuoka Tenjin
Kyushu hub, prescriptions
Pricing structure
Typical Japanese prescription prices (assuming 30% co-pay):
Cold meds (5 days): ¥500-¥1,500
Antibiotics (7 days): ¥800-¥2,500
Blood pressure meds (30 days): ¥1,000-¥3,500
Diabetes meds (30 days): ¥2,000-¥6,000
Cholesterol meds (30 days): ¥1,500-¥4,500
Antidepressants (30 days): ¥1,500-¥5,000
Sleeping pills (30 days): ¥500-¥2,500
Birth control pills (monthly): ¥2,000-¥3,500 (not covered)
ED meds (not covered): ¥1,500-¥2,500/tablet
Vaccines (flu): ¥3,500-¥6,000 (not covered)
OTC: ¥500-¥3,500
Prescription issuance fee (hospital): ¥210-¥420
Dispensing base fee: ¥420-¥730
Medication history management fee: ¥450-¥590
Uninsured: ~3.3x the above (full price)
If an uninsured tourist visits a doctor for a cold, expect ¥6,000-¥15,000 consultation + ¥1,500-¥4,500 meds = about ¥7,500-¥19,500 total.
Tourist and foreigner support
Full English at Nihon Chouzai Roppongi / Azabu-Juban, Ainz & Tulpe Ginza, Kokumin Drug Shinsaibashi, and Sugi Pharmacy Umeda; elsewhere, request English-speaking staff when reserving. Chinese- and Korean-speaking staff at major central stores; translation tablets in peak season. Only prescriptions from doctors licensed in Japan are valid — overseas prescriptions cannot be filled. Tourists needing prescription meds must first see a clinic in Japan and get a new prescription (foreign-friendly clinics in Roppongi / Azabu handle this). OTC is sold without prescription to anyone and is tax-free (10%) on purchases ¥5,000+. For payments, Wise / Revolut debit in JPY beats SWIFT by 0.4-1.5% (varies). VISA / Mastercard / Amex / JCB at nearly all stores; QR payments accepted at major ones.